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National Repository of Grey Literature 1 records found  Search took 0.00 seconds. 
The effect of polymorphism of some enzymes on fatty acid composition in cow´s milk fat
 SVOBODOVÁ, Martina
The aim of the diploma thesis was to determine the genotypes of polymorphic variants of some candidate loci in the AGPAT6 and LEP genes and to evaluate the influence of these polymorphic variants on milk yield and milk fatty acid proportions. Genotypic and allele frequencies of AGPAT6 and LEP were determined in dairy cows (n = 400) of the Czech Fleckvieh breed and its crossbreeds. The PCR / RFLP genotyping method was used. The results showed that the CT (AGPAT6) and MM (LEP) genotypes predominated in the population. The influence of AGPAT6 and LEP polymorphisms on milk yield indicators for the 1st and 2nd lactation could not be demonstrated. The influence of the AGPAT6 genotype on the representation of some short-chain fatty acids has been demonstrated. The effect of the LEP genotype on fatty acid proportions has not been demonstrated. The results of this work make it possible to obtain a more favorable composition of milk fat with respect to human health.
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